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In the functional echocardiographic study, left ventricular fractional shortening (LVFS) was obtained.
The presence of mitral or tricuspid regurgitation was also evaluated.
Correlations were determined by Pearson’s correlation. Area under the curve (AUC) was obtained from receiver operating characteristic curves to assess the most suitable c Tn I cutoff value for adverse neurodevelopmental outcome and for mortality.
A P-value of 48 h after birth in n=5; BSID-II outcome data at 18 months of age not available in n=10).
To investigate whether creatine kinase-MB (CK-MB) and cardiac troponin I (c Tn I) can be used to predict neurodevelopmental outcome at 18 months in infants with perinatal asphyxia (PA).
The diagnostic value of c Tn I to assess myocardial dysfunction was considered as well.
c Tn I was negatively correlated with LVFS (r −0.64; PThis is the first study to report a strict correlation between c Tn I concentration in the first 12 h of life and the medium-term outcome in perinatal asphyxiated newborn infants.
The echocardiogram was obtained with a Toshiba 140 A scanner (Toshiba America Medical Systems, Tustin, CA, USA).
Measurements were made using a 7.5-MHz probe, while a 5-MHz probe was used for Doppler examination.